5 min readMy whole family is always tired. Is that just us, or is it genetic?Family-wide tiredness can be partly genetic and partly shared environment: inherited tendencies in genes like MTHFR (B-vitamin processing) and TMPRSS6 (iron regulation), combined with common Indian vegetarian diets low in iron and B12, often leave whole families running on empty.
Reviewed· 3 sources· 2 genes
4 min readWhat is the one health conversation I should have with my parents?The one health conversation to have with your parents is a clear family medical history: ask which conditions, like diabetes, heart disease, cancers, thalassemia or early deaths, affected close relatives and at what age, because this family history is one of the strongest, cheapest predictors of your own risk.
Reviewed· 3 sources· 1 genes
4 min readShould I worry about diabetes if it runs on one side of my family?Yes, diabetes on one side of your family raises your risk but does not guarantee it: genes like TCF7L2, FTO and KCNJ11 plus shared diet and lifestyle increase odds, and South Asians develop type 2 diabetes earlier and at lower weights, so earlier screening and prevention are worthwhile.
Reviewed· 3 sources· 3 genes
5 min readShould couples get thalassemia screening before marriage?Yes, couples in India should consider thalassemia screening before marriage: beta-thalassemia is caused by HBB gene variants and roughly 1 in 25 Indians is a silent carrier, so if both partners are carriers there is a 1-in-4 chance each pregnancy of a seriously affected child.
Reviewed· 3 sources· 1 genes